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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac9de36d79beaba6ac6bf8cacbb3d774975a10d061a39a54aecb52870e9f1cee' 
  AND token = 'rb6Gm1S0sy3/2HF7rqMJWcFr9C0Y1k6Q2/XH8UVzr1s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}