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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aec5f1ab96ce96fcfd7284485e63c1552ae17d130011f544e2f0ced177f5a463' 
  AND token = 'k9OfI8Mwv58r6wxAY1vlBFbynr0aVpPSvZKo7EkzBt8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}