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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a5f192e76ddd3de99a4986b8fd4590197d1ab66229faee0c3f93b5b4cb2251a' 
  AND token = 'gnRjcPxTwn3Vwzk3d9rskImD7SDSt3WlI0RwFKyAAw0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}