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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5dc93085a5345eea27844a96056e74a17b010dbcbc5d409de61f72b37daa2fc' 
  AND token = 'sUY02yO+Q2uEep9eFC8ycjqoaYoGAjMHLxjX6yJsCwo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}