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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f3bc5197af81c2a4f13344dc74d66ade8d231b5e04d0232711db6f25f8f555a' 
  AND token = 'm8AJZHPDAyAQDIdZQ0SB4Zb18TZSrNYK3WEYNKnZZxY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}