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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f3d1fa7a8bab57a7cd25bf2f6e7997ba1fe70a1eb196cdfd608b4b2b37f6ee0' 
  AND token = 'fPbLoriwPCajQisNxSP8UN552kK8qi2mlsJ4xs+idPc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}