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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4082fa5551429015aa59a24b1c42bc42b93fc2cf4d30c7f721b5d05cd49a56f7' 
  AND token = 'QBuihah47/W4aQ9b9imZrPqnp4cIIYZ5HvwtjKIYRYM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}