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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e386319fc865391426cd9acf0ec4624ab84dafc83074314d93d881111ba4f42b' 
  AND token = 'Zm+ddH4ZzCHdGSuJe+LuBopSkD08SyQqYZTzl1Hj5rI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}