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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d748597aa39fea96984a713f80801929787916248f8e39a0d67cc5795e599c9' 
  AND token = '7VDAC0IZxKKzIZ11Met7dD+WhFfPpDiX5+Wq/xuNkCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}