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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af2829172e9af9662a6090b8ced3681f596409caaa904eaa3519f0022ce4d1f1' 
  AND token = 'DCA9K6Ip6u83+QOsW1nLXB6g66+IO40VNOdwqXQpfVY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}