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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5890c998f26b3487d6dd58bba5d2d8850f1de8e101123ab868b898323f35211f' 
  AND token = 'JICV5036WmfKTvmDC6QUtINGqKRStvBA99VIIWL7cBE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}