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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '463396f6d13bd5bcb056bdb3aaffe35f973ecf89581fa8fe1c3a13740726fec4' 
  AND token = 'KxMyiwbx8/cuBkRHkChBE0k4VGjxANH3VO1oXHdt1C4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}