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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '685bc9a803187e0f49b6baa8172a47c702a8d45c47d3d4cb4770ade1a7a2cc25' 
  AND token = 'HqgwjlznXJKWb6WDs4QUJhwydUlLSeIsJKXcSR3ghcU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}