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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a04f00e096723527b487766e4acc4fb3849e4d697b042705a14490aab2483168' 
  AND token = 'eDwWYyLn2tW33CtrVSDe4V9o6hrx6+FKlxBzzIrqWLo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}