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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5eaf4682855a6182e21e2b2b3595f171ec8b8a85e0d53ed091ff754dea1ffdbe' 
  AND token = 'EdD/WFX1xNPRAU/M4EqZtv/UpFk48jwFNY6XqOHqlaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}