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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d31641719fb64df7263f0975a99297c46e15488496aff741cd64e0448dc1019' 
  AND token = 'XtIim8PeUwE+p5fFSFi2kZCkgVg5FTGkyBusFW423A0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}