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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00c691e4c7dcb0dfcd512b1bca390c23e17665fcf123655adea2bce04ac49336' 
  AND token = 'pgGOL1cnE1a56J/rFzEkJ9NZS1wpQrlRJIsKyQuQGVI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}