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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fc8f692168babdbbe7e413c64c819655370a8cd2de4532887cca8cc028bf586' 
  AND token = '/jhb6+j0UkZe0T5nVcc7XCmfR7UoAmywW7xKFMQQA1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}