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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd45b48f9baf10aef08378a7814674c63a4b21a7c45f5e7267b446ea08bb4edc' 
  AND token = 'WhmCPLOqFDW8U96M7eT5eKwNXWCb4QaV/xsCOBVsgM8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}