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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '005e104d609bbd6dd8b5474e481a46a489f856b4100188964e1510e103956940' 
  AND token = 'oZZP1SPdfoB09zT/gnRd6xHe4EMTLiwFIiGN4L+tUUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}