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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e720057e0cc8ceecb14b2183f6390a9382ec7783cc443bf274d35fac4c3dd551' 
  AND token = 'dBEZs7lQp3TSc/IOTE+3q92GdlSEg9XTSfr5KlWjZpc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}