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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e57eb43a73254fb940ed236af2e153e5443ba820045fb9db10a56e257b47bc0c' 
  AND token = 'hixH0fc1Qa4rcvERjb1EBG23QUIamxIg6fIdHFmh4Bo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}