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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f9fb7d82973282ffc78b976f13cf1411c1434c1478f0ec95df7ed61ade4fd79' 
  AND token = 'u2j3LRge1SjnZbeT3ChXd+CH8gIgIWHfYUzwfCy7IDY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}