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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1327e9490e1ef5481618bd461ab18dce021eb923ac01c731b5b5457658a474dc' 
  AND token = 'Nm1niVWeg3we9Y4sK6BLH8i+z/e5qOJ41MENVLBflzY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}