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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ef5e3050d51d39a8ce458271cb863932e918264171692d9ca81b4a58b3066c4' 
  AND token = 'tl+daMnEZL8UWFDzm3508IelhQty1XINGfCyE+6+APs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}