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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dadff6ba8be1980361158a314a5a238c18646e8946f5c001be2e91dba47e15c9' 
  AND token = 'AvnWrGdWpQ+VOlkL48Gm7SnAgnHlx9E9YUrTFyfkCeI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}