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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3e19c59b5fd995570dc5070e7fcdb862c3685e10899cdd430ed035e04468815' 
  AND token = 'o/nbIyvAJqQPqYVCJJbOlPD7E33NV3O6Ge4+Vb1GBD4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}