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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e6e6ac48fe42148dba8dd0986da18529fb59bb6bcba8cfafb32637020b1092e' 
  AND token = 'DE7fuqxqbEb6KgR7noL2UG0WnXwSVB10R0FE1wB+D8o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}