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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'caa52f74b712a00c57f14e0678d4755e13f08267fafacb30f4f6227026374a7d' 
  AND token = 'uXXL14QIefQ9VaOefS2SXGzET0m7Z7e9LAC/Y7uyI5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}