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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34abeee24bbfc29d1dda1ba7de69d10389d3292b6cb24a3665e06226f8bf61e8' 
  AND token = 'PIslaUk4EkxLQwtku3JZP/W+VkRhYV/ozkP3zE4O3I4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}