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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65886dd86de1b7e1801f4579b2d36700a40b249242109f7f108c333c357ce2ff' 
  AND token = '42c5nzdi6fHfpWAhMxODkob3ZZF0Y3J3E5CBLGk68Gs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}