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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5793ccf0eef564e3e2322e79ce8984d781a74e20ede9c7646dd497f1d8740b6e' 
  AND token = 'adVo93n+qdcx/EqxkkvnAzT4+YIc6Mk6OpAFrVoNUWY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}