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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29737eb80c2bd810b5ad03a6f13177725fcfdf28f76892d1449435ec84cbcadc' 
  AND token = 'APjH9mb5PpxhF+eRlnJicz6fiAY4nPQ6fjjPegj02bQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}