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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cf5b15f4ca5e25764370a5debd5f2203267ed48000757a197f0f7b482960156' 
  AND token = 'QBxyQZRUrIJmD2h2iZczyEoD/GgDer5xZE6gdHvoCNY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}