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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14341bedd22d09aa77e83d788b91d63fbddbbdb6975b00d91621de7765fb8343' 
  AND token = 'xvSWg0K45yioq2140Ko1i4L3UfApdhKrg3y3+5u/bfI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}