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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efc596cb35a34209a9a2f1c911dd477095eb945a06397067f2aa7d7cb20586b6' 
  AND token = 'tPpGNQNuSr4H08ORFcKZqTRm6aQVEVmFE6qZkO4uROE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}