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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cb739c4712fb09414aa7efb75754d2785003a6f705e91c3fc96b89b14b83e46' 
  AND token = 'yj55+a9bGqVuIY9nYmFviYP9dWd8bUE6KK0IZMJt3Y0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}