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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6dc2784e58d5c5e1f540eb6d0727108e669970ca556ef36c6387304d5b369c3c' 
  AND token = 'fKh0d9vlFjSO7f4060cJEsUDGkA6S9QsXcDtMWXWC04=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}