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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e0e53bef0c8ccb430b63614b18e91e80a8ae6f4ef644c1909a7a5307a8f10d2' 
  AND token = 'hlr+KgidEgCRK2QeECWWNIrZ/HvrUP7M2mU7mJ7CLHQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}