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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc9ecbeb51c40e54f5108f5996f7cd411390c08117d4d052c8bd848b0c2d4bb2' 
  AND token = 'VVhqo3AVc00SdkFgLu9YLJWHylsNI+PSmoq6zfZTpL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}