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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e4400715bfbe4059fff04a767f486b802e9c589ddeaf56378892175e14f0cd4' 
  AND token = 'j1ZzLnnI89QigW36BhPaz9FurvvBa/TXrbOyurigYoI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}