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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2ec65251c98aa458f7176cfc7fbd728a8be88e6ecb1522f407e8a4685581a4d' 
  AND token = 'TfmzI5VyJ+eBoLUOKcb2t4z6RbxymG9hqrpit26TKdc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}