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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4463c35752c04826138512eac94a0b16f5fb1428078715331cac7d8c8f47a42' 
  AND token = 'i1vpxkJgU0/3ZfXiKV01+5+PAPyS3ASgg2BKvO8AMPU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}