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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4014cf7f10e4b4ea42e2cd423e378ae0ca3c93341e2d7fd934bb0b9a3ac9e8b3' 
  AND token = 'aTM29PFThvjsGiAOkkXH2VRLUa8uAO8HlO6xCzEPC34=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}