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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '508901cae1084c5fb0d1486080a1a41ee9fc4893df5245200e14b356c14a45ec' 
  AND token = 'I98OippjtEQQ1OCR/pZO75Bs0LBROLNuqPANvQ/Kj+s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}