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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c59572737fe81abb6732cb4ba34056130b3bc37c0757c7c1d4eb31b6c77866a' 
  AND token = 'Dyz/J3Dq25wvfRDjKtSJd75OFu2rFh7daRMVxVGrh+s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}