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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29855211a51453315c54b616d962c6a0327c4c5c68c1299f5112d4a53808f40f' 
  AND token = 'AxDUGC4oaY1+3V8BcJgb8CNoM7pYfoRpVq3XmUp/SO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}