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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2080e2c0accc5a8f6eb5017aa61b2c8c877f8e991901632817d8a5fb906e0f50' 
  AND token = '0WOEBDizpNhYbG7p86ld+y84/8i/UB4fJBtJUqwmI50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}