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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3683b36c3b01a802f9eb7357d1ae51e82faef9ba519b4d304beb0adde477d483' 
  AND token = '40wIM4aEboypcuw2Bj2G/E9DmIQoDpYUYiZYnoc43rU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}