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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd8748fa1e80461cd65aa18b9ba4612c2a4e095886275f17b4c61f9a00851f23' 
  AND token = 'DuuMfCvfFr8hV5aLeHGXVlYkKUlwy5/GOCmr5nm4tx8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}